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1

Immunohistochemical detection of estrogen receptor alpha in male rat spinal cord during development

Kathleen A. Burke, Dolores M. Schroeder, Regina A. Abel, Sue C. Richardson, Robert M. Bigsby, Kenneth P. Nephew

Journal:

Journal of Neuroscience Research

Year:

2000

Language:

english

File:

PDF, 433 KB

english, 2000

2

Epigenetic “bivalently marked” process of cancer stem cell-driven tumorigenesis

Curt Balch, Kenneth P. Nephew, Tim H.-M. Huang, Sharmila A. Bapat

Journal:

Year:

2007

Language:

english

File:

PDF, 135 KB

english, 2007

3

A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer

Fang Fang, Curt Balch, Jeanne Schilder, Timothy Breen, Shu Zhang, Changyu Shen, Lang Li, Carol Kulesavage, Anthony J. Snyder, Kenneth P. Nephew, Daniela E. Matei

Journal:

Year:

2010

Language:

english

File:

PDF, 412 KB

english, 2010

4

A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer

Changyu Shen, Yiwen Huang, Yunlong Liu, Guohua Wang, Yuming Zhao, Zhiping Wang, Mingxiang Teng, Yadong Wang, David A Flockhart, Todd C Skaar, Pearlly Yan, Kenneth P Nephew, Tim HM Huang, Lang Li

Journal:

BMC Systems Biology

Year:

2011

Language:

english

File:

PDF, 5.32 MB

english, 2011

5

Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer

Meng Li, Curt Balch, John S Montgomery, Mikyoung Jeong, Jae Hoon Chung, Pearlly Yan, Tim HM Huang, Sun Kim, Kenneth P Nephew

Journal:

BMC Medical Genomics

Year:

2009

Language:

english

File:

PDF, 1.16 MB

english, 2009

6

An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer

Jaesik Jeong, Lang Li, Yunlong Liu, Kenneth P Nephew, Tim Hui-Ming Huang, Changyu Shen

Journal:

BMC Medical Genomics

Year:

2010

Language:

english

File:

PDF, 718 KB

english, 2010

7

Characterization of molecular and structural determinants of selective estrogen receptor downregulators

Meiyun Fan, Emily L. Rickert, Lei Chen, Syed A. Aftab, Kenneth P. Nephew, Ross V. Weatherman

Journal:

Breast Cancer Research and Treatment

Year:

2007

Language:

english

File:

PDF, 261 KB

english, 2007

8

Alcohol Alters DNA Methylation Patterns and Inhibits Neural Stem Cell Differentiation

Feng C. Zhou, Yokesh Balaraman, MingXiang Teng, Yunlong Liu, Rabindra P. Singh, Kenneth P. Nephew

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2011

Language:

english

File:

PDF, 823 KB

english, 2011

9

Expression of fos and jun Proto-oncogenes in Benign versus Malignant Human Uterine Tissue

Kenneth P Nephew, Carol M Choi, Tara C Polek, Rosalie McBride, Robert M Bigsby, Sohaib A Khan, Nader Husseinzadeh

Journal:

Gynecologic Oncology

Year:

2000

Language:

english

File:

PDF, 482 KB

english, 2000

10

The epigenetics of ovarian cancer drug resistance and resensitization

Curtis Balch, Tim H.-M. Huang, Robert Brown, Kenneth P. Nephew

Journal:

American Journal of Obstetrics and Gynecology

Year:

2004

Language:

english

File:

PDF, 725 KB

english, 2004

11

Effects of SDF-1–CXCR4 signaling on microRNA expression and tumorigenesis in estrogen receptor-alpha (ER-α)-positive breast cancer cells

Lyndsay V. Rhodes, Melyssa R. Bratton, Yun Zhu, Syreeta L. Tilghman, Shannon E. Muir, Virgilio A. Salvo, Chandra R. Tate, Steven Elliott, Kenneth P. Nephew, Bridgette M. Collins-Burow, Matthew E. Buro

Journal:

Experimental Cell Research

Year:

2011

Language:

english

File:

PDF, 775 KB

english, 2011

12

Transcriptional targeting in ovarian cancer cells using the human epididymis protein 4 promoter

Nicholas B Berry, Yong Mee Cho, Maureen A Harrington, Stephen D Williams, John Foley, Kenneth P Nephew

Journal:

Gynecologic Oncology

Year:

2004

Language:

english

File:

PDF, 355 KB

english, 2004

13

What will it take to obtain DNA methylation markers for early cervical cancer detection?

Kenneth P. Nephew

Journal:

Gynecologic Oncology

Year:

2009

Language:

english

File:

PDF, 116 KB

english, 2009

14

Epigenetic therapies for chemoresensitization of epithelial ovarian cancer

Daniela E. Matei, Kenneth P. Nephew

Journal:

Gynecologic Oncology

Year:

2010

Language:

english

File:

PDF, 492 KB

english, 2010

15

Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Alvaro Puga, Sonya J Barnes, Ching-yi Chang, Huan Zhu, Kenneth P Nephew, Sohaib A Khan, Howard G Shertzer

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 533 KB

english, 2000

16

Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome

Guohua Wang, Xin Wang, Yadong Wang, Jack Y Yang, Lang Li, Kenneth P Nephew, Howard J Edenberg, Feng C Zhou, Yunlong Liu

Journal:

Year:

2008

Language:

english

File:

PDF, 318 KB

english, 2008

17

APoissonmixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology

Weixing Feng, Yunlong Liu, Jiejun Wu, Kenneth P Nephew, Tim HM Huang, Lang Li

Journal:

Year:

2008

Language:

english

File:

PDF, 488 KB

english, 2008

18

GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response

Baishen Chen, Xi Rao, Michael G. House, Kenneth P. Nephew, Kevin J. Cullen, Zhongmin Guo

Journal:

Year:

2011

Language:

english

File:

PDF, 780 KB

english, 2011

19

Combinatorial Analysis of Transcription Factor Partners Reveals Recruitment of c-MYC to Estrogen Receptor-α Responsive Promoters

Alfred S.L. Cheng, Victor X. Jin, Meiyun Fan, Laura T. Smith, Sandya Liyanarachchi, Pearlly S. Yan, Yu-Wei Leu, Michael W.Y. Chan, Christoph Plass, Kenneth P. Nephew, Ramana V. Davuluri, Tim H.-M. Hua

Journal:

Year:

2006

Language:

english

File:

PDF, 711 KB

english, 2006

20

EGFR signaling in breast cancer: Bad to the bone

John Foley, Nicole K. Nickerson, Seungyoon Nam, Kah Tan Allen, Jennifer L. Gilmore, Kenneth P. Nephew, David J. Riese II

Journal:

Seminars in Cell & Developmental Biology

Year:

2010

Language:

english

File:

PDF, 648 KB

english, 2010

21

Androgen receptor-driven chromatin looping in prostate cancer

Dayong Wu, Chunpeng Zhang, Yanping Shen, Kenneth P. Nephew, Qianben Wang

Journal:

Trends in Endocrinology & Metabolism

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

22

Studies of dehydroepiandrosterone (DHEA) with the human estrogen receptor in yeast

Kenneth P Nephew, Cameron Q Sheeler, Mark D Dudley, Sheri Gordon, Susan G Nayfield, Sohaib A Khan

Journal:

Molecular and Cellular Endocrinology

Year:

1998

Language:

english

File:

PDF, 162 KB

english, 1998

23

Epigenetic gene silencing in cancer initiation and progression

Kenneth P. Nephew, Tim Hui-Ming Huang

Journal:

Year:

2003

Language:

english

File:

PDF, 252 KB

english, 2003

24

A novel k-mer mixture logistic regression for methylation susceptibility modeling of CpG dinucleotides in human gene promoters

Youngik Yang, Kenneth Nephew, Sun Kim

Journal:

BMC Bioinformatics

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

25

SERPINB2 down-regulation contributes to chemoresistance in head and neck cancer

Huang, Zhiquan, Li, Haigang, Huang, Qi, Chen, Dan, Han, Jingjing, Wang, Lili, Pan, Chanbin, Chen, Weiliang, House, Michael G., Nephew, Kenneth P., Guo, Zhongmin

Journal:

Molecular Carcinogenesis

Year:

2014

Language:

english

File:

PDF, 295 KB

english, 2014

26

An integrative analysis of cellular contexts, miRNAs and mRNAs reveals network clusters associated with antiestrogen-resistant breast cancer cells

Seungyoon Nam, Xinghua Long, ChangHyuk Kwon, Sun Kim, Kenneth P Nephew

Journal:

Year:

2012

Language:

english

File:

PDF, 517 KB

english, 2012

27

A modulator based regulatory network for ERα signaling pathway

Heng-Yi Wu, Pengyue Zheng, Guanglong Jiang, Yunlong Liu, Kenneth P Nephew…

Journal:

Year:

2012

Language:

english

File:

PDF, 782 KB

english, 2012

28

GENOME-WIDE ANALYSIS AND MODELING OF DNA METHYLATION SUSCEPTIBILITY IN 30 BREAST CANCER CELL LINES BY USING CpG FLANKING SEQUENCES

AN, JAEHYUN, KIM, KWANGSOO, RHEE, SUNG-MIN, CHAE, HEEJOON, NEPHEW, KENNETH P., KIM, SUN

Journal:

Journal of Bioinformatics and Computational Biology

Year:

2013

Language:

english

File:

PDF, 606 KB

english, 2013

29

Mo1882 DNA Methylation as a Biomarker System for Pancreatic Adenocarcinoma

Huang, Qi, Golas, Adam A., Guo, Zhongmin, Nephew, Kenneth P., House, Michael G.

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 132 KB

english, 2012

30

A Rationally Designed Histone Deacetylase Inhibitor with Distinct Antitumor Activity against Ovarian Cancer

Yang, Ya-Ting, Balch, Curt, Kulp, Samuel K., Mand, Michael R., Nephew, Kenneth P., Chen, Ching-Shih

Journal:

Year:

2009

Language:

english

File:

PDF, 1.74 MB

english, 2009

31

Aberrant Transforming Growth Factor β1 Signaling and SMAD4 Nuclear Translocation Confer Epigenetic Repression of ADAM19 in Ovarian Cancer

Chan, Michael W.Y., Huang, Yi-Wen, Hartman-Frey, Corinna, Kuo, Chieh-Ti, Deatherage, Daniel, Qin, Huaxia, Cheng, Alfred S.L., Yan, Pearlly S., Davuluri, Ramana V., Huang, Tim H.-M., Nephew, Kenneth P.

Journal:

Year:

2008

Language:

english

File:

PDF, 954 KB

english, 2008

32

Hormonal regulation and expression of the jun-D protooncogene in specific cell types of the rat uterus

Nephew, Kenneth P., Webb, David K., Akcali, Kamil Can, Moulton, Bruce C., Khan, Sohaib A.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1993

Language:

english

File:

PDF, 1.81 MB

english, 1993

33

Strain Differences in Vaginal Responses to the Xenoestrogen Bisphenol A

Xinghua Long, Rosemary Steinmetz, Nira Ben-Jonathan, Andrea Caperell-Grant, Peter C. M. Young, Kenneth P. Nephew and Robert M. Bigsby

Journal:

Environmental Health Perspectives

Year:

2000

Language:

english

File:

PDF, 2.39 MB

english, 2000

34

The Organochlorine o,p'-DDT Plays a Role in Coactivator-Mediated MAPK Crosstalk in MCF-7 Breast Cancer Cells

Melyssa R. Bratton, Daniel E. Frigo, H. Chris Segar, Kenneth P. Nephew, John A. McLachlan, Thomas E. Wiese and Matthew E. Burow

Journal:

Environmental Health Perspectives

Year:

2012

Language:

english

File:

PDF, 2.18 MB

english, 2012

35

Synthesis and Characterization of Fluorescent 4-Hydroxytamoxifen Conjugates with Unique Antiestrogenic Properties

Rickert, Emily L., Oriana, Sean, Hartman-Frey, Cori, Long, Xinghua, Webb, Timothy T., Nephew, Kenneth P., Weatherman, Ross V.

Journal:

Bioconjugate Chemistry

Year:

2010

Language:

english

File:

PDF, 1.88 MB

english, 2010

36

Minireview: Epigenetic Changes in Ovarian Cancer

Balch, Curt, Fang, Fang, Matei, Daniela E., Huang, Tim H.-M., Nephew, Kenneth P.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

37

[IEEE 2011 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) - San Antonio, TX, USA (2011.12.4-2011.12.6)] 2011 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) - An ERα/modulator regulatory network in the breast cancer cells

Wu, Heng-Yi, Wang, Yu, Zheng, P., Jiang, G., Liu, Yunlong, Huang, Tim H. M., Nephew, Kenneth P., Li, Lang

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

38

[IEEE 2011 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) - Atlanta, GA, USA (2011.11.12-2011.11.15)] 2011 IEEE International Conference on Bioinformatics and Biomedicine - BioVLAB-MMIA: A Reconfigurable Cloud Computing Environment for microRNA and mRNA Integrated Analysis

Lee, Hyungro, Yang, Youngik, Chae, Heejoon, Nam, Seungyoon, Choi, Donghoon, Tangchaisin, Patanachai, Herath, Chathura, Marru, Suresh, Nephew, Kenneth P., Kim, Sun

Year:

2011

Language:

english

File:

PDF, 277 KB

english, 2011

39

Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells

Zhuang, Yan, Nguyen, Hong T., Burow, Matthew E., Zhuo, Ying, El-Dahr, Samir S., Yao, Xiao, Cao, Subing, Flemington, Erik K., Nephew, Kenneth P., Fang, Fang, Collins-Burow, Bridgette, Rhodes, Lyndsay V

Journal:

Molecular Carcinogenesis

Year:

2014

Language:

english

File:

PDF, 731 KB

english, 2014

40

TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells

Cardenas, Horacio, Vieth, Edyta, Lee, Jiyoon, Segar, Mathew, Liu, Yunlong, Nephew, Kenneth P, Matei, Daniela

Journal:

Year:

2014

Language:

english

File:

PDF, 4.70 MB

english, 2014

41

Multiple Signaling Pathways Converge on β-Catenin in Thyroid Cancer

Abbosh, Phillip H., Nephew, Kenneth P.

Journal:

Year:

2005

Language:

english

File:

PDF, 105 KB

english, 2005

42

[IEEE 2011 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) - San Antonio, TX, USA (2011.12.4-2011.12.6)] 2011 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) - Empirical bayes model comparisons for differential methylation analysis

Teng, Mingxiang, Wang, Yadong, Liu, Yunlong, Kim, Seongho, Balch, Curt, Nephew, Kenneth P., Li, Lang

Year:

2011

Language:

english

File:

PDF, 372 KB

english, 2011

43

Epigenetic Hypothesis Tests for Methylation and Acetylation in a Triple Microarray System

Li, Lang, Shi, Huidong, Yiannoutsos, Constantin, Huang, Tim Hui-Ming, Nephew, Kenneth P.

Journal:

Journal of Computational Biology

Year:

2005

Language:

english

File:

PDF, 1.03 MB

english, 2005

44

Role of epigenomics in ovarian and endometrial cancers

Balch, Curtis, Matei, Daniela E, Huang, Tim H-M, Nephew, Kenneth P

Journal:

Year:

2010

Language:

english

File:

PDF, 4.52 MB

english, 2010

45

microRNA regulation of mammalian target of rapamycin expression and activity controls estrogen receptor function and RAD001 sensitivity

Martin, Elizabeth C, Rhodes, Lyndsay V, Elliott, Steven, Krebs, Adrienne E, Nephew, Kenneth P, Flemington, Erik K, Collins-Burow, Bridgette M, Burow, Matthew E

Journal:

Molecular Cancer

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

46

A unique histone deacetylase inhibitor alters microRNA expression and signal transduction in chemoresistant ovarian cancer cells

Balch, Curt, Naegeli, Kaleb, Nam, Seungyoon, Ballard, Brett, Hyslop, Alan, Melki, Christina, Reilly, Elizabeth, Hur, Man-Wook, Nephew, Kenneth P.

Journal:

Cancer Biology & Therapy

Year:

2012

Language:

english

File:

PDF, 2.38 MB

english, 2012

47

Inhibition of MCL-1 enhances Lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy

Pandya Martin, Aditi, Mitchell, Clint, Rahmani, Mohammed, Nephew, Kenneth P., Grant, Steven, Dent, Paul

Journal:

Cancer Biology & Therapy

Year:

2009

Language:

english

File:

PDF, 2.83 MB

english, 2009

48

3D culture adds an extra dimension to targeted epigenetic therapies

Ozes, Ali R, Nephew, Kenneth P

Journal:

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

49

Empirical Bayes Model Comparisons for Differential Methylation Analysis

Teng, Mingxiang, Wang, Yadong, Kim, Seongho, Li, Lang, Shen, Changyu, Wang, Guohua, Liu, Yunlong, Huang, Tim H. M., Nephew, Kenneth P., Balch, Curt

Journal:

Comparative and Functional Genomics

Year:

2012

Language:

english

File:

PDF, 1.98 MB

english, 2012

50

Effects of the Endocrine-Disrupting Chemical DDT on Self-Renewal and Differentiation of Human Mesenchymal Stem Cells

Strong, Amy L., Shi, Zhenzhen, Strong, Michael J., Miller, David F.B., Rusch, Douglas B., Buechlein, Aaron M., Flemington, Erik K., McLachlan, John A., Nephew, Kenneth P., Burow, Matthew E., Bunnell,

Journal:

Environmental Health Perspectives

Year:

2014

Language:

english

File:

PDF, 639 KB

english, 2014